Applications
Sample(Cell/DNA) | Applications |
Mammalian | Pre-implantation genetic screening |
Pre-implantation genetic diagnosis | |
Genotyping of transgenic animals | |
Phasing of individual human genomes | |
Genotyping of sperm cell | |
Embryo and stem cell | |
Forensic specimens analysis | |
Typing of transgenic animals | |
Cancer | Somatic genetic variation analysis |
Tumor evolution and development | |
Tumor stem cell | |
Circulating tumor cells | |
Bacteria | Genotyping of microorganism |
Metagenomics study | |
Pathogen analysis |
Cancer Biol Med. 2015 Sep;12(3):184-92. doi: 10.7497/j.issn.2095-3941.2015.0056.
Single-cell analyses of circulating tumor cells.
Chen XX1, Bai F1.
Genetics. 2015 Sep;201(1):31-8. doi: 10.1534/genetics.115.179028. Epub 2015 Jun 26.
A Male-Specific Genetic Map of the Microcrustacean Daphnia pulex Based on Single-Sperm Whole-Genome Sequencing.
Xu S1, Ackerman MS2, Long H2, Bright L2, Spitze K2, Ramsdell JS3, Thomas WK3, Lynch M2.
Annu Rev Genomics Hum Genet. 2015;16:79-102. doi: 10.1146/annurev-genom-090413-025352. Epub 2015 Jun 11.
Single-Cell Whole-Genome Amplification and Sequencing: Methodology and Applications.
Huang L1, Ma F, Chapman A, Lu S, Xie XS.
Fertil Steril. 2014 Dec;102(6):1685-91. doi: 10.1016/j.fertnstert.2014.08.015. Epub 2014 Sep 17.
Validation of multiple annealing and looping-based amplification cycle sequencing for 24-chromosome aneuploidy screening of cleavage-stage
embryos.
Huang J1, Yan L1, Fan W2, Zhao N3, Zhang Y1, Tang F2, Xie XS4, Qiao J5.
Anal Chem. 2014 Oct 7;86(19):9386-90. doi: 10.1021/ac5032176. Epub 2014 Sep 22.
Microfluidic whole genome amplification device for single cell sequencing.
Yu Z1, Lu S, Huang Y.
Cell. 2014 Jul 17;158(2):250-62. doi: 10.1016/j.cell.2014.06.037.
Conducting a microbiome study.
Goodrich JK1, Di Rienzi SC1, Poole AC1, Koren O1, Walters WA2, Caporaso JG3, Knight R4, Ley RE5.
Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21083-8. doi: 10.1073/pnas.1320659110. Epub 2013 Dec 9.
Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients.
Ni X1, Zhuo M, Su Z, Duan J, Gao Y, Wang Z, Zong C, Bai H, Chapman AR, Zhao J, Xu L, An T, Ma Q, Wang Y, Wu M, Sun Y, Wang S, Li Z, Yang X, Yong J, Su XD, Lu Y, Bai F, Xie XS, Wang J.
Cell. 2013 Dec 19;155(7):1492-506. doi: 10.1016/j.cell.2013.11.040.
Genome analyses of single human oocytes.
Hou Y1, Fan W2, Yan L1, Li R1, Lian Y1, Huang J1, Li J1, Xu L1, Tang F3, Xie XS4, Qiao J5.
Science. 2012 Dec 21;338(6114):1622-6. doi: 10.1126/science.1229164.
Genome-wide detection of single-nucleotide and copy-number variations of a single human cell.
Zong C1, Lu S, Chapman AR, Xie XS.
Science. 2012 Dec 21;338(6114):1627-30. doi: 10.1126/science.1229112.
Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing.
Lu S1, Zong C, Fan W, Yang M, Li J, Chapman AR, Zhu P, Hu X, Xu L, Yan L, Bai F, Qiao J, Tang F, Li R, Xie XS.