MALBACTM (Multiple Annealing and Looping-based Amplification Cycles) is a patented whole genome amplification (WGA) technology developed at Harvard University. The special design enables a quasi-linear pre-amplification of the whole genome at the single cell level followed by an exponential amplification, yielding 2-4μg amplification produc suitable for downstream analysis using next-generation sequencing, microarray, or real-time qPCR, etc.